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Plantar fasciitis (PF) accounts for 15% of all foot disorders.More than 10% of the population is affected by itover their lifetime.1-3 Although etiology of PF remainsill-understood, but there are evidences to suggest that it isprobably initiated by repeated microtrauma. Pathologicalchanges are degenerative in nature (although partiallyreversible) and histologically changes, such as, collagennecrosis, angiofibroblastic hyperplasia, chondroid metaplasiaand matrix calcification are seen.4-7The most common presenting symptom of PF is a sharppain of insidious onset with maximal tenderness at theanterior medial border of the calcaneus.8 The pain is typicallyworst on the first few steps in the morning and withinitial steps after prolonged sitting or inactivity, and onexamination, there is mild to severe tenderness on medialcalcaneal tubercle and sometimes, on lateral aspect of heel.Numerous methods have been advocated for treatingPF, including rest, nonsteroidal anti-inflammatory drugs(NSAID),9 night splints, foot orthosis,10 stretching protocols11and extra corporeal shock wave therapy (ESWT).12The use of corticosteroids has been linked to rupture ofplantar fascia especially, after repeated local injections.13Various types of surgical procedures have also been recommendedfor refractory cases.14,15 Platelet-rich plasma(PRP) is an ideal autologous biological blood-derivedproduct, which can be exogenously applied to varioustissues where it releases high concentrations of plateletderived growth factors that enhance wound-healing,bone-healing and also tendon-healing. In addition, PRPpossesses antimicrobial properties that may contributeto the prevention of infections.. When platelets becomeactivated, growth factors are released and initiate thebody’s natural healing response. The PRP injection mightinduce healing at the attachment of fascia at the os calcis.16The purpose of this study was to assess the role andefficacy of autologous PRP injection in treatment of PFand compare it with corticosteroid injection.

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