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     Mangifera indica leaves has been an important component of
indigenous medical systems for over 4,000 years, and the largest fruit-tree
found in India. The usage of Mangifera inidica
leaves as a medicinal agent is dated back to as early as 327 BCE. The presence of some major groups of
phytochemical constituents such ad saponins, anthraquinones, terpenoids, etc,
and therapeutically active components such as mangiferin,
stigmasterol, friedelin, lupeol, etc, have
also been reported from Mangifera indica leaves. There is a paucity of
scientific data in support of their success, although the leaves have been
traditionally used as the antibacterial
and immunomodulatory agent. Mangifera indica leaves are also used as an
antibacterial agent in Nigerian folk herbalism.
To ascertain whether or not there is a scientific basis for this use, the effect of the blood glucose level was assessed in normoglycaemic, glucose-induced
hyperglycaemic and streptozotocin (STZ)
induced diabetic rodents such as Rattus (rat). The aqueous extract given orally
did not alter the blood glucose levels in either normoglycaemic or STZ-induced
(streptozotocin) diabetic rodents specifically Rattus (rat).



Aqueous extracts of Mangifera indica leaves showed remarkable influence on reproductive functions,
wound regeneration and antidiabetic tasks. Alcoholic extracts of Mangifera
indica leaves have been found containing TNF- (Tumor necrosis factor), ILIB
expression and B-lactamase producing enteric
bacterial development.

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     Mangifera indica leaves are equipped with
a broad outer cuticle to avoid the loss of nutrients
and to prevent wetting when it’s
raining. Furthermore, Mangifera indica
leaves are found alternating on the plant stalk to exploit the light energy acquired from the sun. This is because of the
fact that Mangifera indica develops best when exposed to sunlight.

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